Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711168 | 0.80 | SOD1 (0.49) | TSHRKMT2AHTTSOD1 | |
| SCHEMBL9742014 | 0.75 | AKR1B1 (0.46) | ALDH1A1CYP3A4TSHRPOLBALOX15 | |
| SCHEMBL11332537 | 0.74 | TSHR (0.41) | ALDH1A1CYP3A4TSHRMAPK1ALOX15 | |
| SCHEMBL9742200 | 0.73 | POLB (0.44) | ALDH1A1CYP3A4TDP1POLBMEN1 | |
| SCHEMBL7224105 | 0.72 | TSHR (0.37) | ALDH1A1CYP3A4TDP1TSHRPOLB | |
| SCHEMBL9652718 | 0.70 | ALDH1A1 (0.43) | ALDH1A1CYP3A4TDP1TSHRALOX15 | |
| SCHEMBL11876121 | 0.70 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRMAPK1PKM | |
| SCHEMBL11321107 | 0.70 | CA2 (0.38) | ALDH1A1CYP3A4TSHRMAPK1POLB | |
| SCHEMBL11323593 | 0.69 | CA2 (0.46) | — | |
| SCHEMBL7757151 | 0.69 | BRD4 (0.49) | ALDH1A1CYP3A4TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |