Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711140 | 0.82 | ALDH1A1 (0.55) | AKR1B1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL9711209 | 0.79 | AKR1B1 (0.40) | TSHRAKR1B1KMT2AMEN1RAB9A | |
| SCHEMBL9711160 | 0.78 | RAPGEF4 (0.44) | TSHRAKR1B1RAB9AALDH1A1CA1 | |
| SCHEMBL9711217 | 0.73 | ENPP2 (0.45) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7223160 | 0.73 | GAA (0.55) | TSHRKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL7224105 | 0.72 | TSHR (0.37) | TSHRAKR1B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL725771 | 0.71 | PSIP1 (0.52) | TSHRKMT2AALDH1A1CA12CA1 | |
| Methylamine SCHEMBL9711215 | 0.71 | PSIP1 (0.52) | KMT2AALDH1A1CA12CA1CA2 | |
| SCHEMBL9742014 | 0.71 | AKR1B1 (0.46) | TSHRAKR1B1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL9349963 | 0.71 | AKR1B1 (0.36) | TSHRAKR1B1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |