Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213748 | 0.87 | ABCB1 (0.38) | GRM5 | |
| SCHEMBL9215558 | 0.86 | GRM5 (0.41) | SIGMAR1GRM5CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9739164 | 0.85 | HRH3 (0.51) | — | |
| SCHEMBL9216594 | 0.85 | PRMT5 (0.39) | GRM5 | |
| SCHEMBL9209429 | 0.85 | ADRA1B (0.45) | GRM5 | |
| SCHEMBL9204526 | 0.84 | MEN1 (0.39) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL9212507 | 0.84 | GRM5 (0.38) | GRM5 | |
| SCHEMBL9740331 | 0.84 | HRH3 (0.51) | — | |
| SCHEMBL9217306 | 0.84 | ADRA1B (0.46) | GRM5 | |
| SCHEMBL9216938 | 0.83 | PRMT5 (0.40) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |