Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 3/20 | 0.42 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739624 | 0.85 | LMNA (0.46) | USP7TDP1KMT2ALMNANPSR1 | |
| SCHEMBL9711273 | 0.83 | KMT2A (0.37) | USP7USP47TDP1KMT2ALMNA | |
| SCHEMBL9711236 | 0.83 | TDP1 (0.40) | USP7USP47TDP1KMT2ALMNA | |
| SCHEMBL9711235 | 0.72 | PDE7A (0.38) | TDP1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL9711196 | 0.71 | ALDH1A1 (0.40) | TDP1KMT2AALDH1A1MAPTMEN1 | |
| SCHEMBL10980816 | 0.71 | PNMT (0.40) | TDP1KMT2ANPSR1MAPTMEN1 | |
| SCHEMBL9740256 | 0.70 | SMN1; SMN2 (0.40) | TDP1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL8746025 | 0.70 | MAPT (0.37) | TDP1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL6243529 | 0.69 | CYP1A2 (0.53) | TDP1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL1341250 | 0.69 | PDE7A (0.58) | USP7USP47TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |