Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737699 | 0.90 | PTGDR2 (0.46) | KDM4EPTGDR2ALDH1A1APOBEC3AL3MBTL1 | |
| SCHEMBL9738192 | 0.89 | KDM4E (0.39) | KDM4EDRD2ALDH1A1PTGESAPOBEC3A | |
| SCHEMBL9737283 | 0.88 | PTGDR2 (0.47) | KDM4EPTGDR2ALDH1A1APOBEC3A | |
| SCHEMBL9737961 | 0.87 | ALDH1A1 (0.43) | ALDH1A1APOBEC3A | |
| SCHEMBL9738434 | 0.86 | KCNQ3 (0.41) | ALDH1A1APOBEC3AHPGDSMN1; SMN2 | |
| SCHEMBL9737606 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL9737862 | 0.83 | TSPO (0.52) | — | |
| SCHEMBL9738233 | 0.80 | KCNQ3 (0.43) | KDM4EPTGDR2ALDH1A1APOBEC3AHPGD | |
| SCHEMBL9738747 | 0.79 | ALDH1A1 (0.45) | PTGDR2ALDH1A1APOBEC3ASMN1; SMN2 | |
| SCHEMBL9737572 | 0.77 | TSPO (0.45) | KDM4EALDH1A1APOBEC3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |