Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737699 | 0.90 | PTGDR2 (0.46) | PTGDR2KDM4EPTGS2ALDH1A1APOBEC3A | |
| SCHEMBL9737491 | 0.89 | PTGS2 (0.41) | PTGDR2KDM4EGFERPTGS2MYC | |
| SCHEMBL9737634 | 0.88 | KDM4E (0.48) | PTGDR2KDM4EALDH1A1APOBEC3A | |
| SCHEMBL9737572 | 0.87 | TSPO (0.45) | LMNAKDM4EPTGS2MYCALDH1A1 | |
| SCHEMBL9737185 | 0.87 | KCNQ3 (0.41) | KDM4EPTGS2MYCALDH1A1 | |
| SCHEMBL9737163 | 0.86 | ALDH1A1 (0.43) | LMNAKDM4EPTGS2MYCALDH1A1 | |
| SCHEMBL9738542 | 0.84 | TSPO (0.44) | LMNAPOLB | |
| SCHEMBL9737222 | 0.83 | MYC (0.39) | PTGDR2PTGS2MYCRAB9AALDH1A1 | |
| SCHEMBL18116342 | 0.80 | HTR1B (0.44) | LMNA | |
| SCHEMBL9737130 | 0.80 | L3MBTL1 (0.48) | LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |