Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | RXRB | P28702 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743167 | 0.79 | ALDH1A1 (0.36) | GLRA3GLRBHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL5581647 | 0.74 | CYP3A4 (0.48) | GLRA3GLRBALDH1A1CYP3A4TSHR | |
| SCHEMBL9743755 | 0.73 | AKR1C3 (0.37) | ALDH1A1MAPK1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9743140 | 0.72 | ALDH1A1 (0.32) | GLRA3GLRBHCAR2ALDH1A1CYP3A4 | |
| SCHEMBL11555612 | 0.71 | HSD17B10 (0.56) | GLRA3GLRBALDH1A1CYP3A4TSHR | |
| SCHEMBL901084 | 0.65 | ALOX15 (0.70) | GLRA3GLRBALDH1A1CYP3A4TSHR | |
| SCHEMBL7217680 | 0.64 | ALDH1A1 (0.37) | HCAR2ALDH1A1HSD17B10GPR35MAPK1 | |
| SCHEMBL900505 | 0.64 | ALOX15 (0.47) | GLRA3GLRBALDH1A1CYP3A4TSHR | |
| SCHEMBL7745596 | 0.64 | GABRP (0.42) | HCAR2ALDH1A1TSHRALOX15TDP1 | |
| SCHEMBL9675379 | 0.63 | HPGD (0.48) | ALDH1A1TSHRHPGDTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082959-A | Oxidation of alkyl groups substituted on a trialkylsilyl-substituted aromatic ring using oxygen gas and a cobalt and/or manganese compound and a bromide as catalyts | AMOCO CORPORATION (US) | 1992-01-21 | — | — | US | disclosed |