SCHEMBL974314

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL972950	0.90	GRM5 (0.40)	CA12CA1CA2CA4CA7
	SCHEMBL973611	0.89	LMNA (0.37)	GRM5CTSBCTSSCTSKKCNH2
	SCHEMBL973921	0.88	SMN1; SMN2 (0.38)	MAPK1CA12CA1CA2CA4
	SCHEMBL974388	0.86	DRD2 (0.43)	MAPK1CTSBCTSSCTSKKCNH2
	SCHEMBL4703465	0.85	HRH3 (0.42)	GRM5
	SCHEMBL971187	0.85	MTNR1A (0.42)	MAPK1GRM5LMNA
	SCHEMBL973427	0.84	NAAA (0.44)	CTSBCTSSCTSKKCNH2LMNA
	SCHEMBL972442	0.83	CA12 (0.39)	CA12CA1CA2CA4CA7
	SCHEMBL972003	0.83	CTSB (0.36)	CA12CA1CA2CA4CA7
	SCHEMBL974674	0.82	BTK (0.39)	CA12CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.