Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CLPP | Q16740 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743824 | 0.82 | ALDH1A1 (0.44) | CYP19A1ALDH1A1KCNJ1KCNH2 | |
| SCHEMBL7359643 | 0.81 | CYP19A1 (0.52) | SIRT2SIRT1ROCK2ROCK1L3MBTL1 | |
| SCHEMBL26357090 | 0.78 | POLB (0.64) | SIRT2SIRT1ROCK2ROCK1L3MBTL1 | |
| SCHEMBL4182979 | 0.77 | MAPK1 (0.57) | L3MBTL1ALDH1A1HPGD | |
| SCHEMBL7416317 | 0.76 | SIRT2 (0.46) | SIRT2SIRT1ROCK2ROCK1L3MBTL1 | |
| SCHEMBL29809178 | 0.76 | L3MBTL1 (0.54) | SIRT2SIRT1ROCK2ROCK1L3MBTL1 | |
| SCHEMBL7424115 | 0.76 | L3MBTL1 (0.54) | SIRT2SIRT1ROCK2ROCK1L3MBTL1 | |
| SCHEMBL9742340 | 0.75 | KDM4E (0.54) | ROCK2ROCK1ALDH1A1KCNH2 | |
| SCHEMBL3906515 | 0.75 | SLC6A2 (0.47) | SIRT2SIRT1ROCK2ROCK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6886546 | 0.74 | SLC6A2 (0.46) | SIRT2SIRT1ROCK2ROCK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169859-A | Antisecretory or antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1992-12-08 | — | — | US | disclosed |
| WO-1991008203-A1 | NOVEL THIAZOLIDINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1991-06-13 | — | — | WO | disclosed |