Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 14/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 14/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 14/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 14/20 | 0.61 |
| ▸ | CYP2B6 | P20813 | 14/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 14/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BRS3 | P32247 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743301 | 0.90 | CYP2E1 (0.76) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL13651209 | 0.84 | CYP2E1 (0.78) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL9744385 | 0.83 | AR (0.52) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL22468988 | 0.82 | CYP2E1 (0.81) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL8768278 | 0.81 | LMNA (0.79) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL9439554 | 0.80 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL5391945 | 0.78 | CYP1A2 (0.63) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL15693611 | 0.77 | RAB9A (0.76) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL9025916 | 0.77 | CYP2D6 (0.52) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL1101910 | 0.76 | CYP2C19 (0.54) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |