Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743667 | 0.89 | FAAH (0.47) | FAAHCNR1CNR2GPR84LMNA | |
| SCHEMBL9742886 | 0.87 | FAAH (0.54) | FAAHCNR1CNR2GPR84LMNA | |
| SCHEMBL9745593 | 0.86 | MMP1 (0.35) | FAAHCNR1CNR2LMNAMMP1 | |
| SCHEMBL5907621 | 0.84 | FAAH (0.41) | FAAHCNR1CNR2LMNAMMP1 | |
| SCHEMBL14763891 | 0.82 | MMP1 (0.48) | FAAHCNR1CNR2LMNAMMP1 | |
| SCHEMBL6153342 | 0.81 | MMP1 (0.38) | FAAHCNR1CNR2LMNAMMP1 | |
| SCHEMBL451544 | 0.81 | SLC22A6 (0.39) | GPR84LMNAMMP1MMP2MMP3 | |
| SCHEMBL5814007 | 0.79 | LMNA (0.45) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL12560394 | 0.79 | PRKCA (0.41) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL1684075 | 0.78 | GPR84 (0.46) | FAAHCNR1CNR2GPR84LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128252-A | Resolution of optically active esters, transesterification, lipase | CHISSO CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0384189-A2 | Optically active compound and a process for the production thereof | CHISSO CORPORATION (JP) | 1990-08-29 | — | — | EP | disclosed |