Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 7/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 7/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 7/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744385 | 0.90 | AR (0.52) | HPGDSMN1; SMN2RAB9AHSD17B10CYP1A2 | |
| SCHEMBL9743301 | 0.83 | CYP2E1 (0.76) | HPGDRAB9ACYP1A2CYP2E1CYP3A4 | |
| SCHEMBL9439554 | 0.81 | SMN1; SMN2 (0.71) | HPGDSMN1; SMN2RAB9ANPC1AR | |
| SCHEMBL14304934 | 0.80 | RAB9A (0.63) | HPGDSMN1; SMN2RAB9AHSD17B10CYP1A2 | |
| SCHEMBL9743293 | 0.75 | CYP2E1 (0.61) | HPGDSMN1; SMN2RAB9ACYP1A2CYP2E1 | |
| SCHEMBL5112528 | 0.75 | AR (0.70) | HPGDSMN1; SMN2CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL6757973 | 0.75 | HSD17B10 (0.56) | HPGDSMN1; SMN2RAB9AHSD17B10CYP1A2 | |
| SCHEMBL8667804 | 0.74 | HPGD (1.00) | HPGDSMN1; SMN2RAB9AHSD17B10CYP1A2 | |
| SCHEMBL17153982 | 0.73 | HPGD (0.74) | HPGDSMN1; SMN2RAB9AHSD17B10CYP3A4 | |
| SCHEMBL9743830 | 0.72 | ALDH1A1 (0.44) | HPGDSMN1; SMN2RAB9AHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |