Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 2/20 | 0.30 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803456 | 0.91 | GLS2 (0.34) | ALDH1A1SMPD1 | |
| SCHEMBL9160196 | 0.90 | FAAH (0.35) | ALDH1A1SMPD1MAPTELANEZDHHC7 | |
| SCHEMBL9159891 | 0.90 | FAAH (0.35) | ALDH1A1SMPD1MAPTELANEZDHHC7 | |
| SCHEMBL9128899 | 0.89 | LMNA (0.38) | ALDH1A1MAPTELANE | |
| SCHEMBL8985096 | 0.87 | SIGMAR1 (0.34) | ALDH1A1 | |
| SCHEMBL9745100 | 0.86 | — | — | |
| SCHEMBL8985142 | 0.85 | FFAR4 (0.36) | ALDH1A1MAPT | |
| SCHEMBL9127903 | 0.85 | ELANE (0.31) | ELANE | |
| SCHEMBL9327549 | 0.83 | SMPD1 (0.43) | SMPD1 | |
| SCHEMBL9325034 | 0.81 | GLS2 (0.35) | ALDH1A1SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089485-A | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0369811-A2 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |