Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | PPARD | Q03181 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128899 | 0.96 | LMNA (0.38) | LMNAPPARAPPARGALDH1A1MAPT | |
| SCHEMBL9159891 | 0.88 | FAAH (0.35) | PPARAPPARGALDH1A1MAPT | |
| SCHEMBL9160196 | 0.88 | FAAH (0.35) | PPARAPPARGALDH1A1MAPT | |
| SCHEMBL9744651 | 0.85 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL9803456 | 0.84 | GLS2 (0.34) | LTB4RALDH1A1 | |
| SCHEMBL9325309 | 0.84 | LMNA (0.42) | LMNAPPARAPPARGALDH1A1MAPT | |
| SCHEMBL9745062 | 0.83 | PPARG (0.39) | LMNAPPARAPPARGMAPTMAPK1 | |
| SCHEMBL8985108 | 0.82 | PPARA (0.33) | FFAR4FFAR1LMNAPPARAPPARG | |
| SCHEMBL9745263 | 0.81 | LMNA (0.37) | LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL9746538 | 0.81 | LMNA (0.36) | LMNAPPARAPPARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541221-A | Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss | ALLERGAN (US) | 1996-07-30 | — | — | US | disclosed |