Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 3/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160196 | 1.00 | FAAH (0.35) | FAAHCNR1CNR2SMPD1ZDHHC7 | |
| SCHEMBL9128899 | 0.92 | LMNA (0.38) | FAAHCNR1CNR2MAPTELANE | |
| SCHEMBL9744651 | 0.90 | ALDH1A1 (0.32) | SMPD1ZDHHC7MAPTELANEALDH1A1 | |
| SCHEMBL9803456 | 0.89 | GLS2 (0.34) | FAAHSMPD1ALDH1A1 | |
| SCHEMBL8985142 | 0.88 | FFAR4 (0.36) | MAPTALDH1A1PPARGPPARA | |
| SCHEMBL8985096 | 0.85 | SIGMAR1 (0.34) | ALDH1A1 | |
| SCHEMBL9745100 | 0.84 | — | — | |
| SCHEMBL9127903 | 0.83 | ELANE (0.31) | ELANE | |
| SCHEMBL9325309 | 0.82 | LMNA (0.42) | MAPTELANEALDH1A1PPARGPPARA | |
| SCHEMBL9327549 | 0.81 | SMPD1 (0.43) | SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637240-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 3 AND 4-SUBSTITUTED 2(5H)-FURANONES FOR INHIBITING BONE LOSS | ALLERGAN, INC. (US) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993021915-A1 | PHARMACEUTICAL COMPOSITIONS FOR INHIBITING BONE LOSS CONTAINING 3 AND 4-SUBSTITUTED 2(5H)-FURANONES | ALLERGAN, INC. (US) | 1993-11-11 | — | — | WO | disclosed |
| US-5169963-A | Di-(5-hydroxy-2(5H)2-oxo-4-furyl)alkylmethyl-alpha,omega alkanedioates and N,N-bis-(5-hydroxy-2(5H)2-oxo-4-furyl)alkylmethyl-alpha,omega-dialkanoic acid amides as anti-inflammatory agents | ALLERGAN, INC. (US) | 1992-12-08 | — | — | US | disclosed |