Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819670 | 0.87 | CA12 (0.65) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL712594 | 0.81 | CA1 (0.58) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL11289818 | 0.79 | HDAC3 (0.56) | KMT2ALMNAMEN1CA12CA1 | |
| Bromide SCHEMBL7107771 | 0.79 | KMT2A (0.56) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL3729389 | 0.78 | CA12 (0.60) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL28046283 | 0.78 | HDAC3 (0.54) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL3053462 | 0.78 | HDAC2 (0.54) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL5372882 | 0.77 | HDAC3 (0.58) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL364110 | 0.77 | HDAC3 (0.58) | KMT2ALMNAMEN1CA12CA1 | |
| SCHEMBL1750909 | 0.77 | CA12 (0.58) | KMT2ALMNAMEN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232421-B2 | Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | claimed |
| US-7820846-B2 | by phosgenation of an aminobenzoylsulfamic acid amide intermediate; prepared from a p-nitrobenzoyl chloride or benzoate and a sulfamic acid amide and reducing the nitrobenzoylsulfamic acid amide; isocyanates are crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-26 | — | — | US | claimed |
| CN-100368392-C | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their preparation | BASF AG (DE) | 2008-02-13 | — | — | CN | claimed |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | US | claimed |
| US-11219625-B2 | Inhibitors of N-linked glycosylation and methods using same | YALE UNIVERSITY (US) | 2022-01-11 | — | — | US | disclosed |
| US-20190000858-A1 | Inhibitors of N-Linked Glycosylation and Methods Using Same | YALE UNIVERSITY | 2019-01-03 | — | — | US | disclosed |
| WO-2017019540-A2 | INHIBITORS OF N-LINKED GLYCOSYLATION AND METHODS USING SAME | YALE UNIVERSITY (US) | 2017-02-02 | — | — | WO | disclosed |
| US-8541611-B2 | Bifunctional phenyl iso(thio)cyanates, processes and intermediates products for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2013-09-24 | — | — | US | disclosed |
| US-20120271049-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2012-10-25 | — | — | US | disclosed |
| US-8232421-B2 | Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | disclosed |
| US-20110009640-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2011-01-13 | — | — | US | disclosed |
| US-7820846-B2 | by phosgenation of an aminobenzoylsulfamic acid amide intermediate; prepared from a p-nitrobenzoyl chloride or benzoate and a sulfamic acid amide and reducing the nitrobenzoylsulfamic acid amide; isocyanates are crop protection agents | BASF AKTIENGESELLSCHAFT (DE) | 2010-10-26 | — | — | US | disclosed |
| CN-100368392-C | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their preparation | BASF AG (DE) | 2008-02-13 | — | — | CN | disclosed |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | US | disclosed |
| CN-1717388-A | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their preparation | BASF AG (DE) | 2006-01-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190000858-A1 | Inhibitors of N-Linked Glycosylation and Methods Using Same | ENGASE, FUT5, B3GNT2 | KMT2A 3565/4885LMNA 1668/4885MEN1 2573/4885 |
| US-20120271049-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION | TST, IDO1, TMT1A | KMT2A 2541/4885LMNA 3604/4885MEN1 4685/4885 |
| US-20110009640-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | TST, IDO1, IDO2 | KMT2A 2765/4885LMNA 3877/4885MEN1 4740/4885 |
| US-11219625-B2 | Inhibitors of N-linked glycosylation and methods using same | ENGASE, FUT5, B3GNT2 | KMT2A 3565/4885LMNA 1668/4885MEN1 2573/4885 |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | TST, TMT1A, IDO1 | KMT2A 2390/4885LMNA 3280/4885MEN1 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.