Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.57 |
| ▸ | CES1 | P23141 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9591214 | 0.82 | HDAC1 (0.46) | LMNAALDH1A1KDM4ETSHRHDAC1 | |
| SCHEMBL196781 | 0.82 | LMNA (0.52) | CES2CES1LMNAL3MBTL1GLS | |
| SCHEMBL30670484 | 0.82 | LMNA (0.52) | CES2CES1LMNAL3MBTL1GLS | |
| SCHEMBL8127769 | 0.82 | LMNA (0.52) | CES2CES1LMNAL3MBTL1GLS | |
| SCHEMBL196782 | 0.82 | LMNA (0.52) | CES2CES1LMNAL3MBTL1GLS | |
| SCHEMBL11751222 | 0.79 | TDP1 (0.42) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL7595932 | 0.79 | PGR (0.47) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL7763783 | 0.78 | CES2 (0.59) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL10781088 | 0.77 | LMNA (0.57) | CES2CES1LMNATDP1L3MBTL1 | |
| SCHEMBL17784348 | 0.77 | CES2 (0.57) | CES2CES1LMNATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236628-A1 | Inhibition of the 5-lipoxygenase pathway | SMITHKLINE BEECHAM CORPORATION (US) | 1987-09-16 | — | — | EP | claimed |
| CN-118900677-A | Dental adhesive composition | 株式会社GC | 2024-11-05 | — | — | CN | disclosed |
| CN-110832039-A | Dielectric ink composition | 阿尔法装配解决方案公司 | 2020-02-21 | — | — | CN | disclosed |
| EP-0236628-B1 | INHIBITION OF THE 5-LIPOXYGENASE PATHWAY | SMITHKLINE BEECHAM CORPORATION (US) | 1992-12-02 | — | — | EP | disclosed |
| EP-0236628-A1 | Inhibition of the 5-lipoxygenase pathway | SMITHKLINE BEECHAM CORPORATION (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4686231-A | 4,5-DIARYL-2-SUBSTITUTED-IMIDAZOLE | SMITHKLINE BECKMAN CORPORATION (US) | 1987-08-11 | — | — | US | disclosed |