Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL713577 | 0.80 | SCN9A (0.46) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL977040 | 0.79 | SCN9A (0.34) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL31118371 | 0.78 | SCN9A (0.45) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL3544332 | 0.77 | POLB (0.33) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL3540540 | 0.77 | POLB (0.34) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL3059734 | 0.76 | SCN9A (0.43) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL25046395 | 0.76 | SCN9A (0.42) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL25047105 | 0.75 | SCN9A (0.43) | SCN9APOLBAPEX1CYP2C19 | |
| SCHEMBL712255 | 0.75 | SCN9A (0.45) | SCN9ACYP2C19 | |
| SCHEMBL972982 | 0.73 | HPGD (0.44) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541611-B2 | Bifunctional phenyl iso(thio)cyanates, processes and intermediates products for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8541611-B2 | Bifunctional phenyl iso(thio)cyanates, processes and intermediates products for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2013-09-24 | — | — | US | disclosed |
| US-8357695-B2 | Hydrates of 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)-pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide | BASF SE (DE) | 2013-01-22 | — | — | US | disclosed |
| EP-2537829-A1 | Aminobenzoylsulfamides and their preparation | BASF SE (DE) | 2012-12-26 | — | — | EP | disclosed |
| US-20120271049-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2012-10-25 | — | — | US | disclosed |
| US-20120271049-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION | BASF AKTIENGESELLSCHAFT (DE) | 2012-10-25 | — | — | US | disclosed |
| EP-2079714-B1 | HYDRATES OF 2-CHLORO-5-Ý3,6-DIHYDRO-3-METHYL-2,6-DIOXO-4-(TRIFLUORO-METHYL)-1-(2H)-PYRIMIDINYL¨-4-FLUORO-N-ÝÝMETHYL-(1-METHYLETHYL)-AMINO¨SULPHONYL¨BENZAMIDE | BASF SE (DE) | 2012-09-26 | — | — | EP | disclosed |
| EP-1560810-B1 | BIFUNCTIONAL PHENYLISO(THIO)CYANATES; METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BASF SE (DE) | 2012-08-01 | — | — | EP | disclosed |
| US-8232421-B2 | Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | disclosed |
| US-8232421-B2 | Bifunctional phenyl ISO (THIO) cyanates, processes and intermediates for their preparation | BASF AKTIENGESELLSCHAFT (DE) | 2012-07-31 | — | — | US | disclosed |
| US-20100035905-A1 | Hydrates of 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)-pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide | BASF Agro B.V. (CH) | 2010-02-11 | — | — | US | disclosed |
| EP-2079714-A1 | HYDRATES OF 2-CHLORO-5-Ý3,6-DIHYDRO-3-METHYL-2,6-DIOXO-4-(TRIFLUORO-METHYL)-1-(2H)-PYRIMIDINYL¨-4-FLUORO-N-ÝÝMETHYL-(1-METHYLETHYL)-AMINO¨SULPHONYL¨BENZAMIDE | BASF SE (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008043836-A1 | HYDRATES OF 2-CHLORO-5-[3,6-DIHYDRO-3-METHYL-2,6-DIOXO-4-(TRIFLUORO-METHYL)-1-(2H)-PYRIMIDINYL]-4-FLUORO-N-[[METHYL-(1-METHYLETHYL)-AMINO]SULPHONYL]BENZAMIDE | BASF SE (DE) | 2008-04-17 | — | — | WO | disclosed |
| EP-1692115-B1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-20060293520-A1 | Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | US | disclosed |
| EP-1692115-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-23 | — | — | EP | disclosed |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | BASF AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | US | disclosed |
| EP-1560810-A1 | BIFUNCTIONAL PHENYLISO(THIO)CYANATES; METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2005-08-10 | — | — | EP | disclosed |
| WO-2005054208-A1 | METHOD FOR PRODUCING 3-PHENYL(THIO)URACILS AND 3-PHENYLDITHIOURACILS | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | WO | disclosed |
| WO-2004039768-A1 | BIFUNCTIONAL PHENYLISO(THIO)CYANATES; METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293520-A1 | Mehtod for producing 3-phenyl(thio)uracils and 3-phenyldithiouracils | HPRT1, TH, METTL3 | SCN9A 2711/4885POLB 2308/4885APEX1 368/4885 |
| US-20120271049-A1 | BIFUNCTIONAL PHENYL ISO (THIO) CYANATES, PROCESSES AND INTERMEDIATES PRODUCTS FOR THEIR PREPARATION | TST, IDO1, TMT1A | SCN9A 3631/4885POLB 1336/4885APEX1 50/4885 |
| US-20060004220-A1 | Bifunctional phenyliso(thio)cyanates, processes and intermediates products for their Preparation | TST, TMT1A, IDO1 | SCN9A 3755/4885POLB 1447/4885APEX1 38/4885 |
| US-20100035905-A1 | Hydrates of 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)-pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide | DHX15, DHX35, BROX | SCN9A 1123/4885POLB 1622/4885APEX1 1503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.