Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 11/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745148 | 0.84 | ADORA3 (0.48) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9745279 | 0.83 | CACNA1B (0.47) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9745985 | 0.76 | HIF1A (0.55) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9502243 | 0.76 | ADORA3 (0.73) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11771568 | 0.74 | ABCC1 (0.61) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3026966 | 0.72 | ABCC1 (0.71) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9744733 | 0.72 | CACNA1B (0.55) | CACNA1BADORA3 | |
| SCHEMBL9745152 | 0.70 | CACNA1B (0.51) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7266484 | 0.70 | CACNA1B (0.73) | CACNA1BADORA3 | |
| SCHEMBL11773488 | 0.69 | CACNA1F (0.56) | HIF1AMEN1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215250-B1 | 2-SUBSTITUTED-1,4-DIHYDROPYRIDINES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-30 | — | — | EP | disclosed |
| US-4845113-A | USEFUL IN RADICAL SCAVENGING THERAPY | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-07-04 | — | — | US | disclosed |