SCHEMBL9746254

SCHEMBL9746254

Nc1ccc(Oc2ccc(S(=O)(=O)c3ccccc3)c(Oc3ccc(N)cc3)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.49
ALDH1A1 P00352 5/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
GAA P10253 2/20 0.46
MAPT P10636 2/20 0.46
MITF O75030 1/20 0.46
GFER P55789 1/20 0.46
NLRP1 Q9C000 1/20 0.46
NOD2 Q9HC29 1/20 0.46
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
NLRP3 Q96P20 1/20 0.45
HTR6 P50406 3/20 0.44
HTT P42858 1/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
SOS1 Q07889 1/20 0.42
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10342827 0.93 MAOA (0.46) MAOAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL9747934 0.89 MAOB (0.54) ALDH1A1MEN1KMT2ASMN1; SMN2GAA
SCHEMBL5831246 0.86 HTR6 (0.56) MAOAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL2798440 0.84 HTR6 (0.50) ALDH1A1SMN1; SMN2GAAHTR6HTT
SCHEMBL9472814 0.81 MAOA (0.63) MAOAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL28723448 0.80 SMN1; SMN2 (0.59) MAOAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL9874252 0.80 MAOA (0.46) MAOAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL6712174 0.80 MAOB (0.47) MAOAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5013393 0.78 ALDH1A1 (0.47) MAOAALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL9422355 0.78 HTR6 (0.47) MAOAALDH1A1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112989-A Process for producing unsaturated mono and dicarboxylic acid imide compound MATSUSHITA ELECTRIC WORKS LTD. (JP) 1992-05-12 US disclosed
EP-0387381-A1 Process for producing unsaturated dicarboxylic acid imide compound MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1990-09-19 EP disclosed