SCHEMBL9746433

SCHEMBL9746433

[CH2]CC#CC(=O)OC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.34
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27546342 0.83 CTSK (0.33) CTSK
SCHEMBL27014757 0.80 CTSK (0.35) CTSKDGAT1
SCHEMBL1088806 0.80 CTSK (0.35) CTSKDGAT1
SCHEMBL3977407 0.78 CTSK (0.34) CTSKDGAT1
SCHEMBL1414348 0.78 DGAT1 (0.40) CTSKDGAT1
SCHEMBL1088319 0.78 SPHK1 (0.42) CTSK
SCHEMBL1089166 0.77 SPHK1 (0.35) CTSKDGAT1
SCHEMBL1088416 0.77 CTSK (0.38) CTSKDGAT1
SCHEMBL29257241 0.76 GAA (0.31) CTSK
SCHEMBL9604817 0.75 CTSK (0.33) CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0204285-B1 IMIDAZOHETEROCYCLIC COMPOUNDS PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-01-15 EP disclosed
US-4725601-A Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-02-16 US disclosed
CN-86104313-A The preparation method of Imidazoheterocyclic compounds 1987-03-04 CN disclosed
EP-0204285-A1 Imidazoheterocyclic compounds processes for preparation thereof and pharmaceutical compositions comprising them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-12-10 EP disclosed