Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.49 |
| ▸ | CA12 | O43570 | 11/20 | 0.49 |
| ▸ | CA1 | P00915 | 11/20 | 0.49 |
| ▸ | CA9 | Q16790 | 11/20 | 0.49 |
| ▸ | CA5A | P35218 | 6/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.47 |
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | CA6 | P23280 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 5/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691455 | 0.80 | TDP1 (0.52) | GAAHSP90AA1CRHBPCRHR2ESR1 | |
| SCHEMBL9747070 | 0.79 | ALDH1A1 (0.42) | CA2CA12CA1CA9MEN1 | |
| SCHEMBL18829453 | 0.78 | CYP3A4 (0.44) | MEN1KMT2AGAAMAPTHSP90AA1 | |
| SCHEMBL6121655 | 0.78 | CYP3A4 (0.44) | LMNAMEN1KMT2AKDM4EMAPT | |
| SCHEMBL1911571 | 0.76 | CA2 (0.68) | CA2CA12CA1CA9CA5A | |
| SCHEMBL12170111 | 0.75 | MEN1 (0.48) | LMNAMEN1KMT2AGAAMAPT | |
| SCHEMBL23909541 | 0.75 | CA2 (0.66) | CA2CA12CA1CA9CA5A | |
| SCHEMBL9747251 | 0.74 | VCAM1 (0.43) | CA2CA1VCAM1MEN1KMT2A | |
| SCHEMBL23909577 | 0.73 | CA2 (0.64) | CA2CA12CA1CA9CA5A | |
| SCHEMBL14058836 | 0.73 | CA2 (0.58) | CA2CA12CA1CA9CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |