Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 12/20 | 0.62 |
| ▸ | RARB | P10826 | 12/20 | 0.62 |
| ▸ | RARG | P13631 | 12/20 | 0.62 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.62 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | BLVRB | P30043 | 1/20 | 0.56 |
| ▸ | RXRA | P19793 | 2/20 | 0.55 |
| ▸ | RXRB | P28702 | 2/20 | 0.55 |
| ▸ | RXRG | P48443 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5888067 | 0.89 | RARB (0.66) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8458958 | 0.87 | RXRA (0.69) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL9748966 | 0.86 | RARA (0.50) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL9748378 | 0.85 | FFAR1 (0.58) | CYP26A1CYP26B1CYP3A4 | |
| SCHEMBL5680243 | 0.83 | RARB (0.71) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL9746945 | 0.83 | RXRA (0.80) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL10542551 | 0.81 | CYP26A1 (0.43) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8461595 | 0.80 | RARB (0.63) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8677671 | 0.80 | CYP3A4 (0.61) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL2391376 | 0.77 | RARB (1.00) | RARARARBRARGCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |
| US-4826969-A | SKIN AND EYE DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-05-02 | — | — | US | disclosed |