Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.58 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.58 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.49 |
| ▸ | GNA15 | P30679 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747007 | 0.85 | RARA (0.62) | CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL21776768 | 0.81 | CYP26B1 (0.83) | FFAR1CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL29605538 | 0.81 | CYP26B1 (0.83) | FFAR1CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL9748966 | 0.78 | RARA (0.50) | CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL5888067 | 0.78 | RARB (0.66) | CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL10542551 | 0.78 | CYP26A1 (0.43) | FFAR1CYP26B1CYP26A1CYP3A4FFAR4 | |
| SCHEMBL13027011 | 0.77 | CYP26A1 (0.78) | CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL9748654 | 0.76 | CYP26B1 (0.57) | CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL8458958 | 0.76 | RXRA (0.69) | CYP26B1CYP26A1CYP3A4 | |
| SCHEMBL6004955 | 0.76 | CYP26A1 (0.53) | CYP26B1CYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | claimed |