Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011898 | 0.73 | NPC1 (0.34) | ABL1TLR7 | |
| SCHEMBL9011897 | 0.66 | NPC1 (0.33) | TLR7 | |
| SCHEMBL17852387 | 0.65 | POLB (0.51) | — | |
| SCHEMBL8351967 | 0.61 | ICMT (0.44) | GPR139 | |
| SCHEMBL8784834 | 0.61 | TBXAS1 (0.47) | CYP19A1CYP11B1 | |
| SCHEMBL9012424 | 0.60 | ADRA2A (0.42) | — | |
| SCHEMBL17449711 | 0.57 | PDE2A (0.44) | — | |
| SCHEMBL19494345 | 0.56 | CYP19A1 (0.44) | ABL1BCRMAOAMAOBCYP19A1 | |
| SCHEMBL20526653 | 0.56 | HRH4 (0.43) | — | |
| SCHEMBL13197062 | 0.56 | GABRA1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |