Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9011890 | 0.88 | ADRA1D (0.40) | NPC1RAB9A | |
| SCHEMBL6528639 | 0.79 | IDO1 (0.33) | TLR7 | |
| SCHEMBL9011898 | 0.78 | NPC1 (0.34) | NPC1RAB9ATLR7PDE3BPDE3A | |
| SCHEMBL9012164 | 0.78 | RIPK1 (0.44) | NPC1RAB9A | |
| SCHEMBL9011960 | 0.76 | ITK (0.30) | — | |
| SCHEMBL9329176 | 0.73 | ADRA1D (0.40) | — | |
| SCHEMBL9012410 | 0.72 | HTR1A (0.32) | — | |
| SCHEMBL9011980 | 0.71 | ADRA1D (0.38) | RAB9APDE3BPDE3A | |
| SCHEMBL9012324 | 0.71 | PDE3B (0.31) | PDE3BPDE3A | |
| SCHEMBL9012474 | 0.70 | ADRA1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523317-A | ADMINISTERING IMIDAZOLE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0354788-B1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO (JP) | 1995-09-13 | — | — | EP | disclosed |
| EP-0633026-A1 | Use of imidazole derivative for antihypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0584588-A1 | Anti-ulcer composition containing imidazole derivative | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
| US-5180836-A | Antiulcer agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5082943-A | Antiulcer | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0354788-A1 | Novel imidazole derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |