SCHEMBL9747411

SCHEMBL9747411

COc1ccc2c(oc(=O)c3ccccc32)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.65
ALDH1A1 P00352 3/20 0.57
MAPT P10636 2/20 0.57
HPGD P15428 2/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2C9 P11712 1/20 0.57
CYP2C19 P33261 1/20 0.57
MAOB P27338 3/20 0.56
ESR2 Q92731 3/20 0.56
MCL1 Q07820 4/20 0.56
ESR1 P03372 1/20 0.49
TERT O14746 1/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
KDM4E B2RXH2 1/20 0.48
LMNA P02545 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9748258 0.88 ESR2 (0.55) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL7987277 0.78 ESR2 (0.70) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL9747985 0.78 MAOA (0.65) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL26779757 0.76 ESR2 (0.57) MAOAALDH1A1MAPTCYP2C9CYP2C19
SCHEMBL4397355 0.75 MAOB (0.67) MAOAALDH1A1HPGDMAOBMCL1
SCHEMBL28662147 0.74 ALDH1A1 (0.49) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL30623098 0.73 ALDH1A1 (1.00) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL4650053 0.73 ALDH1A1 (1.00) MAOAALDH1A1MAPTHPGDCYP3A4
SCHEMBL6825266 0.72 ESR2 (1.00) MAOAALDH1A1HPGDESR2ESR1
SCHEMBL15984891 0.72 MCL1 (1.00) MAOAALDH1A1MAPTHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104894-A Ellagic acid analogues UNIVERSITY OF GUELPH (CA) 1992-04-14 US claimed
US-5104894-A Ellagic acid analogues UNIVERSITY OF GUELPH (CA) 1992-04-14 US disclosed