SCHEMBL9748258

SCHEMBL9748258

COc1ccc2c(oc(=O)c3ccccc32)c1O.O=c1oc2c(O)c(O)ccc2c2ccc(O)c(O)c12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 6/20 0.55
ESR1 P03372 3/20 0.55
MAOA P21397 3/20 0.53
PKLR P30613 1/20 0.48
GALNT2 Q10471 1/20 0.48
GALNT1 Q10472 1/20 0.48
GALNT3 Q14435 1/20 0.48
GALNT10 Q86SR1 1/20 0.48
GALNT13 Q8IUC8 1/20 0.48
GALNT6 Q8NCL4 1/20 0.48
GALNT14 Q96FL9 1/20 0.48
MAOB P27338 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
MCL1 Q07820 2/20 0.46
TERT O14746 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747411 0.88 MAOA (0.65) ESR2ESR1MAOAMAOBALDH1A1
SCHEMBL7987277 0.81 ESR2 (0.70) ESR2ESR1MAOAPKLRGALNT2
SCHEMBL7984298 0.80 ESR2 (0.75) ESR2ESR1PKLRGALNT2GALNT1
SCHEMBL9747985 0.74 MAOA (0.65) ESR2ESR1MAOAMAOBALDH1A1
SCHEMBL7982381 0.70 PTGS2 (0.57) ESR2ESR1MAOAALDH1A1CYP3A4
SCHEMBL30629209 0.70 ESR2 (0.66) ESR2ESR1PKLRGALNT2GALNT1
SCHEMBL6825266 0.70 ESR2 (1.00) ESR2ESR1MAOAALDH1A1HPGD
SCHEMBL26766942 0.70 ESR2 (0.66) ESR2ESR1PKLRGALNT2GALNT1
SCHEMBL9749884 0.69 LMNA (0.50) ESR2ESR1MAOAALDH1A1CYP3A4
SCHEMBL13924669 0.68 MAOA (0.47) ESR2ESR1MAOAALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104894-A Ellagic acid analogues UNIVERSITY OF GUELPH (CA) 1992-04-14 US disclosed