SCHEMBL4650053

SCHEMBL4650053

COc1ccc2c(=O)cc(-c3ccccc3)oc2c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
CYP3A4 P08684 4/20 1.00
CYP2C19 P33261 4/20 1.00
HPGD P15428 3/20 1.00
MAPT P10636 3/20 1.00
CYP2C9 P11712 2/20 1.00
TERT O14746 4/20 0.73
KDM4E B2RXH2 4/20 0.68
HSD17B10 Q99714 3/20 0.68
CYP19A1 P11511 3/20 0.68
TP53 P04637 2/20 0.68
MEN1 O00255 1/20 0.68
IKBKB O14920 1/20 0.68
ALOX15 P16050 1/20 0.68
MAOA P21397 1/20 0.68
MAOB P27338 1/20 0.68
MAPK1 P28482 1/20 0.68
KMT2A Q03164 1/20 0.68
NTRK2 Q16620 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30623098 1.00 ALDH1A1 (1.00) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL6612048 0.85 TERT (0.88) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL4649487 0.85 CYP3A4 (0.76) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL6612829 0.84 TERT (0.86) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL6613454 0.84 TERT (1.00) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL31632541 0.84 CYP3A4 (0.72) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL31632545 0.84 CYP3A4 (0.72) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL6803222 0.82 TERT (0.74) ALDH1A1CYP3A4CYP2C19HPGDMAPT
8-Methoxyflavone SCHEMBL26180800 0.82 ALDH1A1 (0.74) ALDH1A1CYP3A4CYP2C19HPGDMAPT
SCHEMBL31632248 0.82 CYP2C19 (0.69) ALDH1A1CYP3A4CYP2C19HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
US-20250161459-A1 TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-05-22 US claimed
WO-2025038971-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT A NUCLEOBASE, 2' POSITION, OR 3' POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
WO-2025038960-A1 OLIGONUCLEOTIDES CONTAINING A LIGAND AT AN INTERNAL POSITION ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
WO-2025038970-A1 MODIFIED OLIGONUCLEOTIDES CONTAINING MULTIPLE OLIGONUCLEOTIDES ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
CN-118973616-A Trkb ligand conjugated compounds and uses thereof 阿达尔克斯制药有限公司 2024-11-15 CN claimed
WO-2023154896-A2 TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF ADARX PHARMACEUTICALS, INC. (US) 2023-08-17 WO claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN disclosed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN disclosed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN disclosed
US-20250161459-A1 TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-05-22 US disclosed
WO-2025038970-A1 MODIFIED OLIGONUCLEOTIDES CONTAINING MULTIPLE OLIGONUCLEOTIDES ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO disclosed
EP-1373244-A2 SUBSTITUTED BENZOPYRANONES AS TELOMERASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-02 EP disclosed
WO-2003057210-A1 COMPOSITIONS AND METHODS FOR INCREASING CELL PROLIFERATION COMPRISING A FLAVONOID KIMBERLY-CLARK WORLDWIDE, INC. (US) 2003-07-17 WO disclosed
US-20030125264-A1 Methods For Treating Wounds KIMBERLY-CLARK WORLDWIDE, INC. 2003-07-03 US disclosed
US-20020160983-A1 Substituted benzopyranones as telomerase inhibitors PHARMACIA ITALIA S.P.A. (IT) 2002-10-31 US disclosed
WO-2002074036-A2 SUBSTITUTED BENZOPYRANONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161459-A1 TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF NTRK2, NTRK1, BDNF ALDH1A1 1653/4885CYP3A4 4808/4885CYP2C19 4643/4885
US-20020160983-A1 Substituted benzopyranones as telomerase inhibitors TERT, TERF2, TERF2IP ALDH1A1 1247/4885CYP3A4 3385/4885CYP2C19 3703/4885
US-20030125264-A1 Methods For Treating Wounds FGF2, MMP1, FIBP ALDH1A1 2440/4885CYP3A4 3010/4885CYP2C19 2389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.