Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744480 | 0.84 | PIN1 (0.32) | TPH1 | |
| SCHEMBL9744275 | 0.73 | PIN1 (0.33) | TPH1 | |
| SCHEMBL9036054 | 0.68 | BRAF (0.40) | — | |
| SCHEMBL9474294 | 0.68 | PTGER4 (0.32) | — | |
| SCHEMBL9596553 | 0.64 | RAB9A (0.39) | — | |
| SCHEMBL9596094 | 0.63 | CCR1 (0.39) | — | |
| SCHEMBL9042225 | 0.63 | F10 (0.37) | — | |
| SCHEMBL9597441 | 0.63 | CCR1 (0.38) | — | |
| SCHEMBL14201637 | 0.63 | KMT2A (0.36) | — | |
| SCHEMBL9036056 | 0.62 | LOXL2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5133798-A | Certain herbicidal 1,2,4-triazolo[4,5-b]pyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-28 | — | — | US | disclosed |
| EP-0453065-A1 | Triazolopyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |