Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.30 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744275 | 0.88 | PIN1 (0.33) | PIN1TPH1HPGDALDH1A1CYP3A4 | |
| SCHEMBL9747467 | 0.84 | TPH1 (0.30) | TPH1 | |
| SCHEMBL10473955 | 0.75 | TDP1 (0.37) | PIN1HPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9474036 | 0.74 | ALDH1A1 (0.45) | PIN1HPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10471827 | 0.72 | MEN1 (0.40) | PIN1HPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10473225 | 0.72 | MERTK (0.39) | PIN1HPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10474036 | 0.72 | MERTK (0.39) | PIN1HPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9037261 | 0.71 | MEN1 (0.46) | PIN1ALDH1A1TDP1LMNAATM | |
| SCHEMBL10472248 | 0.71 | TDP1 (0.46) | PIN1HPGDALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10472092 | 0.71 | TDP1 (0.39) | PIN1HPGDALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5133798-A | Certain herbicidal 1,2,4-triazolo[4,5-b]pyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-28 | — | — | US | disclosed |