Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744480 | 0.88 | PIN1 (0.32) | PIN1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL9743913 | 0.82 | PKM (0.42) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9854877 | 0.77 | TDP1 (0.55) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10474161 | 0.75 | TDP1 (0.45) | PIN1MEN1KMT2ATDP1TTR | |
| SCHEMBL10473602 | 0.75 | MEN1 (0.41) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL9474036 | 0.73 | ALDH1A1 (0.45) | PIN1MEN1KMT2ATDP1TTR | |
| SCHEMBL9747467 | 0.73 | TPH1 (0.30) | TPH1 | |
| SCHEMBL9037261 | 0.73 | MEN1 (0.46) | PIN1MEN1KMT2ATDP1TTR | |
| SCHEMBL10472248 | 0.73 | TDP1 (0.46) | PIN1MEN1KMT2ATDP1TTR | |
| SCHEMBL10474194 | 0.73 | TDP1 (0.37) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5133798-A | Certain herbicidal 1,2,4-triazolo[4,5-b]pyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-28 | — | — | US | disclosed |
| EP-0453065-A1 | Triazolopyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |