SCHEMBL9747669

SCHEMBL9747669

Cc1[nH]c2c(Cl)c(Cc3ccccc3)ncc2c1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.38
OPRD1 P41143 1/20 0.38
SMO Q99835 1/20 0.37
AHR P35869 2/20 0.35
LTB4R Q15722 1/20 0.35
AOC3 Q16853 1/20 0.35
KDM4E B2RXH2 3/20 0.35
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.34
HTR2C P28335 1/20 0.34
EGFR P00533 1/20 0.34
LMNA P02545 2/20 0.33
HPGD P15428 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
PARP1 P09874 1/20 0.33
AR P10275 1/20 0.33
HPGDS O60760 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1736684 0.75 CYP1A2 (0.46) AHRLTB4RKDM4EMAPTALDH1A1
Hydrochloric Acid SCHEMBL1737887 0.74 CYP1A2 (0.45) AHRLTB4RKDM4EMAPTALDH1A1
SCHEMBL9737888 0.70 SMO (0.40) OPRM1OPRD1SMOLTB4RMAPT
SCHEMBL2771388 0.67 AOC3 (0.49) AOC3MAPTLMNACYP2C9CYP2C19
SCHEMBL7476572 0.66 L3MBTL1 (0.41) MAPTALDH1A1LMNAHPGDCYP1A2
Hydrochloric Acid SCHEMBL2768923 0.66 AOC3 (0.51) AOC3MAPTALDH1A1LMNACYP2C9
SCHEMBL1735804 0.66 CYP1A2 (0.45) AHRKDM4EMAPTALDH1A1EGFR
SCHEMBL29044391 0.65 CALM1 (0.41) SMOLTB4RAOC3MAPTHTR2C
SCHEMBL31457102 0.65 CALM1 (0.41) SMOLTB4RAOC3MAPTHTR2C
SCHEMBL23716436 0.65 TRPM8 (0.41) SMOMAPTALDH1A1LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992006979-A1 NEW DIAZINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-04-30 WO disclosed