Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9669306 | 0.77 | KCNJ11 (0.46) | ABCC9ABCC8KCNJ11KCNJ8ALDH1A1 | |
| SCHEMBL8892128 | 0.74 | KAT2B (0.52) | MAPT | |
| SCHEMBL9365444 | 0.72 | LMNA (0.45) | GPR35MAPT | |
| SCHEMBL9364633 | 0.70 | SAE1 (0.54) | CA1CA2ABCC9KCNJ11ALDH1A1 | |
| SCHEMBL9364688 | 0.69 | KMT2A (0.57) | PDK1PDK2PDK3PDK4ALDH1A1 | |
| SCHEMBL9362784 | 0.67 | L3MBTL1 (0.47) | ALDH1A1 | |
| SCHEMBL13037656 | 0.65 | CA2 (0.55) | NCEH1F2PLGPLAUKLKB1 | |
| SCHEMBL9362554 | 0.64 | HSP90AA1 (0.39) | NCEH1ALDH1A1MAPT | |
| SCHEMBL12310183 | 0.64 | CA2 (0.53) | NCEH1F2PLGPLAUKLKB1 | |
| SCHEMBL12320904 | 0.64 | CA2 (0.53) | NCEH1F2PLGPLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |