Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748582 | 0.83 | NR4A1 (0.44) | PGRMAPTRAB9ASRD5A2BRD4 | |
| SCHEMBL24112226 | 0.73 | PGR (0.49) | PGRSMN1; SMN2MAPTTSHRCACNB4 | |
| SCHEMBL24112933 | 0.73 | PGR (0.49) | PGRSMN1; SMN2MAPTTSHRCACNB4 | |
| SCHEMBL9747889 | 0.73 | AKR1C3 (0.44) | MAPTRAB9ANPC1HTTMEN1 | |
| SCHEMBL195020 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2HSD17B10MAPTRAB9ASRD5A2 | |
| SCHEMBL30185351 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2HSD17B10MAPTRAB9ASRD5A2 | |
| SCHEMBL9748600 | 0.70 | KMT2A (0.41) | PGRMAPTRAB9ASRD5A2NPC1 | |
| SCHEMBL29829303 | 0.70 | RECQL (0.71) | SMN1; SMN2HSD17B10MAPTRAB9ASRD5A2 | |
| SCHEMBL5080596 | 0.70 | RECQL (0.71) | SMN1; SMN2HSD17B10MAPTRAB9ASRD5A2 | |
| SCHEMBL9748589 | 0.68 | KMT2A (0.39) | PGRMAPTRAB9ASRD5A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221753-B1 | TRANSDERMAL TREATMENT FOR PAIN AND INFLAMMATION WITH 2-AMINO-3-AROYLBENZENEACETIC ACIDS, SALTS AND ESTERS | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1992-01-08 | — | — | EP | disclosed |
| US-4683242-A | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0221753-A2 | Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-05-13 | — | — | EP | disclosed |