Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805924 | 0.73 | GABRA1 (0.34) | GABRA1GABRB2 | |
| SCHEMBL878561 | 0.73 | KDM4E (0.40) | GABRA1GABRB2MEN1KMT2A | |
| SCHEMBL9651154 | 0.72 | ALDH1A1 (0.39) | GABRA1GABRB2MEN1MAPTKMT2A | |
| SCHEMBL9748012 | 0.69 | ALDH1A1 (0.40) | MEN1KMT2A | |
| SCHEMBL11667850 | 0.65 | KDM4E (0.50) | MEN1MAPTKMT2A | |
| SCHEMBL1655684 | 0.65 | ALOX5 (0.39) | MEN1MAPTKMT2A | |
| SCHEMBL6111306 | 0.64 | ALOX5 (0.49) | MEN1MAPTKMT2A | |
| SCHEMBL16553402 | 0.63 | GABRA1 (0.36) | GABRA1GABRB2MEN1MAPTKMT2A | |
| SCHEMBL9499567 | 0.63 | — | — | |
| SCHEMBL725361 | 0.63 | GABRA1 (0.34) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |