Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785028 | 0.71 | NPC1 (0.48) | ALDH1A1NPC1RAB9APOLBLMNA | |
| SCHEMBL878561 | 0.69 | KDM4E (0.40) | ALDH1A1NPC1RAB9AHPGDLMNA | |
| SCHEMBL9748019 | 0.69 | GABRA1 (0.33) | KMT2AMEN1 | |
| SCHEMBL11285673 | 0.68 | NOTUM (0.36) | ALDH1A1NPC1RAB9AHPGDPOLB | |
| SCHEMBL24074659 | 0.67 | ALDH1A1 (0.57) | ALDH1A1POLBTSHRHSD17B10LMNA | |
| SCHEMBL23146937 | 0.67 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AHPGDPOLB | |
| SCHEMBL9247111 | 0.66 | KDM4E (0.40) | ALDH1A1HPGDTSHRCASP1CASP7 | |
| SCHEMBL16672350 | 0.66 | LMNA (0.57) | ALDH1A1HPGDLMNAGAA | |
| SCHEMBL18010785 | 0.65 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AHPGDPOLB | |
| SCHEMBL10815985 | 0.65 | CYP4F2 (0.41) | ALDH1A1POLBTSHRHSD17B10NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |