SCHEMBL9748164

SCHEMBL9748164

FCOc1cc(Cl)ccc1N=C=S

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.31
MIF P14174 1/20 0.31
S1PR4 O95977 1/20 0.31
SLC6A4 P31645 1/20 0.30
HTR6 P50406 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528908 0.84 TDP1 (0.42) S1PR4SLC6A4HTR6HPGDTSHR
SCHEMBL30298623 0.72 HTR2B (0.33) MIFSLC6A4HPGD
SCHEMBL6596126 0.72 HTR2B (0.33) MIFSLC6A4HPGD
SCHEMBL1021797 0.71 ITGB3 (0.43) MIFSLC6A4HPGDTSHR
SCHEMBL29668125 0.71 ITGB3 (0.43) MIFSLC6A4HPGDTSHR
SCHEMBL1021879 0.70 HTR2B (0.34) APLNRMIFSLC6A4HPGD
SCHEMBL22469823 0.69 ALPL (0.34) SLC6A4HPGD
SCHEMBL8232189 0.68 ALDH1A1 (0.46) S1PR4HPGDTSHR
SCHEMBL7766240 0.68 S1PR4 (0.37) S1PR4SLC6A4
SCHEMBL1457266 0.68 ALDH1A1 (0.42) APLNRMIFSLC6A4HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5131946-A Herbicides SCHERING AKTIENGESELLSCHAFT (DE) 1992-07-21 US disclosed