Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30298623 | 1.00 | HTR2B (0.33) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL1021879 | 0.86 | HTR2B (0.34) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL11553684 | 0.85 | ALOX5 (0.36) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL163398 | 0.80 | TDP1 (0.38) | HTR2BALDH1A1CYP3A4HPGDSLC6A4 | |
| SCHEMBL29574363 | 0.80 | TDP1 (0.38) | HTR2BALDH1A1CYP3A4HPGDSLC6A4 | |
| SCHEMBL29668125 | 0.79 | ITGB3 (0.43) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL156589 | 0.79 | ALDH1A1 (0.38) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL1021797 | 0.79 | ITGB3 (0.43) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL29564714 | 0.79 | ALDH1A1 (0.38) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 | |
| SCHEMBL3287519 | 0.78 | ABCB11 (0.34) | HTR2BABCB11ALDH1A1NR3C1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139286-B1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AG (DE) | 2025-02-26 | — | — | EP | disclosed |
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | BAYER AKTIENGESELLSCHAFT (DE) | 2024-04-23 | — | — | US | disclosed |
| US-20230167078-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| US-20230139936-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-04 | — | — | US | disclosed |
| CN-1171879-C | Herbicidal 3-aryl-1,2,4-triazole derivative | 拜尔公司 | 2004-10-20 | — | — | CN | disclosed |
| EP-1120411-B1 | 4-Aryl-1,2,4-triazolidinedione derivatives and their use as herbicides | BAYER CROPSCIENCE AG (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-6743755-B2 | HERBICIDAL COMPOSITION WHICH HAS A CONTENT OF AT LEAST ONE N-ARYL NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OF THE GENERAL METHOD OF COMBATING UNDESIRABLE PLANTS WHICH COMPRISES ALLOWING AN N-ARYL NITROGEN-CONTAINING HETEROCYCLIC | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-01 | — | — | US | disclosed |
| US-20030208073-A1 | Substituted N-aryl nitrogen-containing heterocyclic compounds | LINKER KARL-HEINZ (DE) | 2003-11-06 | — | — | US | disclosed |
| US-20030144522-A1 | Substituted N-aryl nitrogen-containing heterocyclic compounds | LINKER KARL-HEINZ (DE) | 2003-07-31 | — | — | US | disclosed |
| CN-1090623-C | 3-aryl-1, 2, 4-triazole derivatives having herbicidal properties | BAYER AG (DE) | 2002-09-11 | — | — | CN | disclosed |
| US-4868321-A | FOR HERBICIDES | FMC CORPORATION (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0252982-A4 | HERBICIDAL 1-ARYL-4-SUSTITUTTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF. | FMC CORP (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0252982-A1 | HERBICIDAL 1-ARYL-4-SUSTITUTTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC Corporation (US) | 1988-01-20 | — | — | EP | disclosed |
| CN-86108880-A | 1-aryl-4 substituting group-1,4-dihydro-5H-tetrazolium-5-ketone and sulfur analogs weedicide thereof | — | 1987-07-22 | — | — | CN | disclosed |
| WO-1987003873-A1 | HERBICIDAL 1-ARYL-4-SUBSTITUTED-1,4-DIHYDRO-5H-TETRAZOL-5-ONES AND SULFUR ANALOGS THEREOF | FMC CORPORATION (US) | 1987-07-02 | — | — | WO | disclosed |
| US-4409018-A | HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| US-4380466-A | HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-04-19 | — | — | US | disclosed |
| EP-0041256-A1 | Hexahydroisoindol derivatives, process for producing said compounds and herbicides containing said compounds | Takeda Chemical Industries, Ltd. (JP) | 1981-12-09 | — | — | EP | disclosed |
| EP-0040849-A1 | Hexahydroisoindole derivatives, process for producing said compounds and herbicides containing said compounds | Takeda Chemical Industries, Ltd. (JP) | 1981-12-02 | — | — | EP | disclosed |
| US-4138242-A | Novel 2-aryl-2,3,5,6,7,8-hexahydro-3-thioxoimidazo-[1,5-a-]pyridin-1(BaH)-ones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139936-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | DGKZ, DGKA, DGKG | HTR2B 4278/4885ABCB11 4447/4885ALDH1A1 3985/4885 |
| US-20030208073-A1 | Substituted N-aryl nitrogen-containing heterocyclic compounds | NAT1, CYP1B1, CYP1A1 | HTR2B 167/4885ABCB11 1838/4885ALDH1A1 138/4885 |
| US-20230167078-A1 | SUBSTITUTED AMINOTHIAZOLES AS DGKZETA INHIBITORS FOR IMMUNE ACTIVATION | DGKZ, DGKA, DGKG | HTR2B 4278/4885ABCB11 4447/4885ALDH1A1 3985/4885 |
| US-20030144522-A1 | Substituted N-aryl nitrogen-containing heterocyclic compounds | NAT1, CYP1B1, CYP1A1 | HTR2B 167/4885ABCB11 1838/4885ALDH1A1 138/4885 |
| US-11964953-B2 | Substituted aminothiazoles as DGKzeta inhibitors for immune activation | DGKZ, DGKA, DGKG | HTR2B 4278/4885ABCB11 4447/4885ALDH1A1 3985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.