Sugi Predict

Sugi Predict / Compounds / SCHEMBL7301852

SCHEMBL7301852

SCHEMBL7301852

O=C(CCc1ccccc1)c1ccc(O)cc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.66
▸ CYP19A1 P11511 2/20 0.66
▸ MAPT P10636 2/20 0.66
▸ SLC5A1 P13866 2/20 0.66
▸ SLC5A2 P31639 2/20 0.66
▸ ESR1 P03372 2/20 0.56
▸ SHBG P04278 1/20 0.56
▸ ESR2 Q92731 1/20 0.56
▸ HTT P42858 1/20 0.55
▸ CYP1A1 P04798 1/20 0.55
▸ CYP1B1 Q16678 1/20 0.55
▸ HSP90AB1 P08238 1/20 0.54
▸ MEN1 O00255 3/20 0.54
▸ KMT2A Q03164 3/20 0.54
▸ ALDH1A1 P00352 2/20 0.54
▸ TSHR P16473 2/20 0.54
▸ KDM4E B2RXH2 1/20 0.54
▸ SLC16A3 O15427 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ TTR P02766 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30065457 1.00 GAA (0.66) GAACYP19A1MAPTSLC5A1SLC5A2
SCHEMBL7295307 0.90 HTT (0.60) GAACYP19A1MAPTSLC5A1SLC5A2
Davidigenin SCHEMBL30291870 0.90 CYP19A1 (0.70) GAACYP19A1MAPTSLC5A1SLC5A2
Davidigenin SCHEMBL750182 0.90 CYP19A1 (0.70) GAACYP19A1MAPTSLC5A1SLC5A2
SCHEMBL9748707 0.87 CYP19A1 (0.66) GAACYP19A1MAPTSLC5A1SLC5A2
SCHEMBL10829584 0.84 TSHR (0.63) GAACYP19A1MAPTSLC5A1SLC5A2
SCHEMBL20576964 0.84 MAPT (0.54) GAACYP19A1MAPTSLC5A1SLC5A2
SCHEMBL644294 0.84 ALOX15 (0.56) GAACYP19A1MAPTSLC5A1SLC5A2
SCHEMBL3677145 0.84 MPO (0.61) GAACYP19A1MAPTSLC5A1SLC5A2
SCHEMBL30497946 0.83 ESR1 (0.80) GAAMAPTESR1SHBGESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023278394-A1 POLYCATIONIC SALTS OF PHENOLIC COMPOUNDS AND USES THEREOF FIRMENICH INCORPORATED (US) 2023-01-05 — — WO disclosed
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 — — US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 — — US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 — — US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 — — EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 — — CN disclosed
CN-106999380-B Hair deforming agent 花王株式会社 2020-05-05 — — CN disclosed
US-20190290564-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-09-26 — — US disclosed
US-20190254943-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-08-22 — — US disclosed
US-20190224093-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-07-25 — — US disclosed
WO-2017207799-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 — — WO disclosed
WO-2017207768-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2017-12-07 — — WO disclosed
WO-2017207767-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 — — WO disclosed
WO-2017207786-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2017-12-07 — — WO disclosed
EP-3228300-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 — — EP disclosed
EP-3228302-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 — — EP disclosed
US-20160220510-A1 ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2016-08-04 — — US disclosed
US-20160220510-A1 ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2016-08-04 — — US disclosed
US-5151420-A Cardiovascular disorders ORION CORPORATION/ORION PHARMACEUTICA (FI) 1992-09-29 — — US disclosed
EP-0359439-A1 Substituted pyridazinones ORION-YHTYMÄ OY (FI) 1990-03-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C GAA 2165/4885CYP19A1 675/4885MAPT 2002/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR GAA 2430/4885CYP19A1 283/4885MAPT 2150/4885
US-20190254943-A1 HAIR COSMETIC COMPOSITION CUTA, POLR1C, GRHPR GAA 2430/4885CYP19A1 283/4885MAPT 2150/4885
US-20160220510-A1 ANTIBIOTIC COMPOUNDS THAT INHIBIT BACTERIAL PROTEIN SYNTHESIS AARS1, EPRS1, EEF1G GAA 836/4885CYP19A1 4043/4885MAPT 1595/4885
US-20190224093-A1 HAIR COSMETIC COMPOSITION CUTA, GRHPR, POLR1C GAA 2165/4885CYP19A1 675/4885MAPT 2002/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 GAA 2213/4885CYP19A1 1471/4885MAPT 1209/4885
US-20190290564-A1 HAIR COSMETIC COMPOSITION GRHPR, POLR1C, TYR GAA 2622/4885CYP19A1 402/4885MAPT 2362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.