Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148747 | 0.82 | — | — | |
| SCHEMBL268870 | 0.82 | — | — | |
| SCHEMBL268869 | 0.82 | — | — | |
| Piperidine SCHEMBL28047155 | 0.78 | FFAR3 (0.50) | ALDH1A1FFAR3 | |
| Piperidine SCHEMBL7686112 | 0.78 | ALDH1A1 (0.45) | ALDH1A1FFAR3 | |
| Piperidine SCHEMBL6861563 | 0.77 | FFAR3 (0.56) | ALDH1A1FFAR3 | |
| Pyrrolidine SCHEMBL10413119 | 0.77 | FFAR3 (0.56) | ALDH1A1FFAR3 | |
| Pyrrolidine SCHEMBL28213560 | 0.77 | FFAR3 (0.56) | ALDH1A1FFAR3 | |
| Piperidine SCHEMBL1274941 | 0.77 | FFAR3 (0.56) | ALDH1A1FFAR3 | |
| Pyrrolidine SCHEMBL28213593 | 0.76 | ALDH1A1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0223744-B1 | FLAVONE DERIVATIVES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1992-03-11 | — | — | EP | disclosed |
| US-4806534-A | SMOOTH MUSCLE RELAXANT, CALCIUM ANTAGONIST | RECORDATI S.A., CHEMICAL & PHARMACEUTICAL COMPANY (CH) | 1989-02-21 | — | — | US | disclosed |
| EP-0223744-A2 | Flavone derivatives | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1987-05-27 | — | — | EP | disclosed |