SCHEMBL974907

SCHEMBL974907

Cc1nc2ncnn2c(NC2CCCC2)c1-c1c(F)cc(F)cc1F

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CDK2 P24941 1/20 0.38
GSK3B P49841 1/20 0.38
PDE2A O00408 3/20 0.37
TSHR P16473 2/20 0.37
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL978477 0.86 KMT2A (0.36) MAPK1MEN1KMT2ACDK2GSK3B
SCHEMBL31020441 0.84 MAPK1 (0.39) MAPK1MEN1KMT2APDE2ATSHR
SCHEMBL5593138 0.84 MAPK1 (0.39) MAPK1MEN1KMT2ACDK2GSK3B
SCHEMBL5593106 0.83 TSHR (0.38) MAPK1MEN1KMT2ACDK2GSK3B
SCHEMBL8386886 0.82 PDE2A (0.41) MEN1KMT2APDE2A
SCHEMBL975027 0.81 MAPK1 (0.44) MAPK1MEN1KMT2ATSHRALOX15
SCHEMBL5593523 0.80 PDE2A (0.39) MEN1KMT2ACDK2GSK3BPDE2A
SCHEMBL976565 0.79 PDE2A (0.43) MAPK1PDE2A
SCHEMBL8385664 0.79 ENPP1 (0.51) MAPK1MEN1KMT2ATSHRALOX15
SCHEMBL5593250 0.79 MAPK1 (0.40) MAPK1MEN1KMT2ATSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8974806-B2 Method for producing aqueous active substance compositions of active substances that are hardly soluble in water BASF AKTIENGESELLSCHAFT (DE) 2015-03-10 US disclosed
US-8741324-B2 Liquid pesticide compositions BASF SE (DE) 2014-06-03 US disclosed
US-8728504-B2 Process for solubilizing hydrophobic active ingredients in aqueous medium BASF SE (DE) 2014-05-20 US disclosed
EP-2676680-A1 Use of hydrophobin polypeptides as penetration enhancers BASF SE (DE) 2013-12-25 EP disclosed
US-8497230-B2 Solid crop protection agents containing polyalkoxylate, method for their production and use thereof BASF AKTIENGESELLSCHAFT (DE) 2013-07-30 US disclosed
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER BASF SE (DE) 2013-05-16 US disclosed
EP-1763300-B1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF SE (DE) 2013-05-15 EP disclosed
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT BASF SE (DE) 2011-12-22 US disclosed
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM BASF SE (DE) 2011-08-11 US disclosed
WO-2011095449-A1 METHOD FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AN AQUEOUS SOLUTION BASF SE (DE) 2011-08-11 WO disclosed
EP-1773121-A1 LIQUID PESTICIDE COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2007-04-18 EP disclosed
EP-1763300-A1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF AKTIENGESELLSCHAFT (DE) 2007-03-21 EP disclosed
EP-1756188-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2007-02-28 EP disclosed
WO-2006125647-A1 METHOD FOR DETERMINING RESIDUES IN PLASTICS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed
WO-2006125644-A1 METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed
WO-2006084680-A1 POLYMER COMPOSITIONS AND THEIR USE IN THE PRODUCTION OF ACTIVE OR EFFECTIVE INGREDIENT COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-08-17 WO disclosed
WO-2006015791-A2 METHOD FOR PRODUCING AQUEOUS ACTIVE SUBSTANCE COMPOSITIONS OF ACTIVE SUBSTANCES THAT ARE HARDLY SOLUBLE IN WATER BASF AKTIENGESELLSCHAFT (DE) 2006-02-16 WO disclosed
WO-2006002984-A1 LIQUID PESTICIDE COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 2006-01-12 WO disclosed
WO-2006000592-A1 USE OF ETHER GROUP-CONTAINING POLYMERS AS SOLUBILIZERS BASF AKTIENGESELLSCHAFT (DE) 2006-01-05 WO disclosed
WO-2005121201-A1 AMPHIPHILIC POLYMER COMPOSITIONS AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2005-12-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110312497-A1 USE OF HYDROPHOBIN AS A SPREADING AGENT PFN1, DSTN, CHN2 MAPK1 3589/4885MEN1 958/4885KMT2A 4413/4885
US-20110195844-A1 PROCESS FOR SOLUBILIZING HYDROPHOBIC ACTIVE INGREDIENTS IN AQUEOUS MEDIUM IDUA, PHOSPHO1, HDHD5 MAPK1 477/4885MEN1 2014/4885KMT2A 1567/4885
US-20130123108-A1 ACTIVE SUBSTANCE COMPOSITION COMPRISING AT LEAST ONE NITROGEN ATOM-CONTAINING, HYPERBRANCHED POLYMER NOS1, NOS3, NPSR1 MAPK1 2382/4885MEN1 1633/4885KMT2A 3704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.