Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852546 | 0.89 | PTGS1 (0.36) | PTGS1KMT2ACXCR1CXCR2ALDH1A1 | |
| SCHEMBL9748843 | 0.84 | PTGS1 (0.38) | PTGS1KMT2ACXCR1CXCR2ALDH1A1 | |
| SCHEMBL9852499 | 0.81 | KMT2A (0.40) | PTGS1KMT2ACXCR1CXCR2ALDH1A1 | |
| SCHEMBL9749314 | 0.77 | HSD17B10 (0.40) | KMT2AALDH1A1HSD17B10FFAR1HPGD | |
| SCHEMBL9749147 | 0.75 | MAPK1 (0.40) | KMT2AALDH1A1MEN1HSD17B10MAPT | |
| SCHEMBL10685641 | 0.73 | PTGS1 (0.39) | PTGS1KMT2ACXCR1CXCR2ALDH1A1 | |
| SCHEMBL9750280 | 0.72 | PTPRG (0.45) | KMT2AALDH1A1MEN1RAB9ALMNA | |
| SCHEMBL9748133 | 0.71 | HSD17B10 (0.32) | ALDH1A1HSD17B10MAPTMAPK1HPGD | |
| SCHEMBL15737155 | 0.69 | KMT2A (0.43) | PTGS1KMT2ACXCR1CXCR2ALDH1A1 | |
| SCHEMBL9627261 | 0.68 | KDM4E (0.43) | KMT2AALDH1A1MEN1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0409055-A1 | Cephalosporin derivatives and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-23 | — | — | EP | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |