Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9748003 | 0.77 | PTGS1 (0.36) | HSD17B10CYP1A2KMT2AFFAR1ALDH1A1 | |
| SCHEMBL9750280 | 0.76 | PTPRG (0.45) | CYP1A2CYP2C19KMT2AALDH1A1GAA | |
| SCHEMBL10688331 | 0.75 | CYP1A2 (0.43) | HSD17B10CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL9749147 | 0.73 | MAPK1 (0.40) | HSD17B10KMT2AFFAR1ALDH1A1ALOX15 | |
| SCHEMBL9852576 | 0.68 | KDM4E (0.34) | KDM4EL3MBTL1 | |
| SCHEMBL10872677 | 0.68 | KDM4E (0.42) | KDM4EL3MBTL1 | |
| SCHEMBL10432526 | 0.63 | KDM4E (0.57) | HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL10432894 | 0.60 | KDM4E (0.35) | CYP1A2CYP3A4KDM4E | |
| SCHEMBL9706738 | 0.60 | ALOX15 (0.49) | HSD17B10CYP1A2KMT2AFFAR1ALDH1A1 | |
| SCHEMBL5632525 | 0.60 | CYP1A2 (0.46) | HSD17B10CYP1A2CYP3A4CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |