Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750226 | 0.79 | KDM4E (0.45) | L3MBTL1ALDH1A1PPARAPRKAG1PRKAA2 | |
| SCHEMBL12964364 | 0.75 | PLA2G4A (0.46) | PLA2G4AL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL12964413 | 0.72 | PLA2G4A (0.48) | PLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL3114211 | 0.72 | L3MBTL1 (0.50) | POLBPLA2G4AL3MBTL1ALDH1A1GAA | |
| SCHEMBL9749240 | 0.72 | L3MBTL1 (0.41) | PLA2G4AL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL6825656 | 0.72 | L3MBTL1 (0.48) | PLA2G4AL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL9749369 | 0.71 | ALDH1A1 (0.44) | HTTPOLBALDH1A1GAAPPARA | |
| SCHEMBL1246147 | 0.70 | PLA2G4A (0.45) | POLBPLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL16503358 | 0.69 | PLA2G4A (0.44) | POLBPLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL16503356 | 0.69 | PLA2G4A (0.44) | POLBPLA2G4AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |