Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3114211 | 0.83 | L3MBTL1 (0.50) | L3MBTL1PRKAG1PRKAA2PRKAB1KDM4E | |
| SCHEMBL9481442 | 0.83 | L3MBTL1 (0.46) | L3MBTL1PRKAG1PRKAA2PRKAB1KDM4E | |
| SCHEMBL21962990 | 0.82 | RAB9A (0.57) | ALDH1A1TSHRTDP1 | |
| SCHEMBL9749568 | 0.78 | L3MBTL1 (0.43) | L3MBTL1PRKAG1PRKAA2PRKAB1ALDH1A1 | |
| SCHEMBL12964364 | 0.78 | PLA2G4A (0.46) | L3MBTL1PRKAG1PRKAA2PRKAB1KDM4E | |
| SCHEMBL14805662 | 0.78 | L3MBTL1 (0.46) | L3MBTL1PRKAG1PRKAA2PRKAB1KDM4E | |
| SCHEMBL6786585 | 0.76 | ALDH1A1 (0.63) | L3MBTL1KDM4EALDH1A1ACHEHPGDS | |
| SCHEMBL9750229 | 0.75 | APEX1 (0.53) | L3MBTL1PRKAG1PRKAA2PRKAB1KDM4E | |
| SCHEMBL12964413 | 0.75 | PLA2G4A (0.48) | L3MBTL1ALDH1A1PLA2G4A | |
| SCHEMBL9750226 | 0.75 | KDM4E (0.45) | L3MBTL1PRKAG1PRKAA2PRKAB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383499-A2 | METHOD OF IMMUNOMODULATION USING THIONE-FORMING DISULFIDES | Grassetti, Davide R. (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002055080-A2 | METHOD OF IMMUNOMODULATION USING THIONE-FORMING DISULFIDES | GRASSETTI DAVIDE R (US) | 2002-07-18 | — | — | WO | disclosed |