Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749075 | 0.78 | KDM4E (0.44) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9749568 | 0.75 | L3MBTL1 (0.43) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL31742493 | 0.73 | GAA (0.42) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL29285032 | 0.71 | HDAC3 (0.36) | ALDH1A1HPGDLMNA | |
| SCHEMBL9749270 | 0.70 | L3MBTL1 (0.39) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA | |
| SCHEMBL24917646 | 0.69 | SHMT1 (0.37) | SMN1; SMN2ALDH1A1HPGDMAPTLMNA | |
| SCHEMBL1565803 | 0.69 | HSD17B10 (0.46) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL8538009 | 0.69 | SHMT1 (0.35) | RAB9AGAAMEN1KMT2APOLB | |
| SCHEMBL18169169 | 0.69 | RAB9A (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1758691 | 0.68 | HSD17B10 (0.44) | SMN1; SMN2RAB9ANPC1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |