Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749499 | 0.85 | CRHBP (0.52) | LMNAALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL13059466 | 0.82 | MAPT (0.49) | LMNAALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL10502068 | 0.82 | NT5E (0.51) | LMNAALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL9748282 | 0.79 | CYP3A4 (0.49) | LMNAALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL10422313 | 0.77 | NHERF1 (0.55) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9750234 | 0.77 | L3MBTL1 (0.39) | LMNAALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10892147 | 0.77 | ALDH1A1 (0.44) | LMNAALDH1A1MEN1KMT2ACYP19A1 | |
| Hydrochloric Acid SCHEMBL10892135 | 0.76 | ALDH1A1 (0.56) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL22499569 | 0.74 | MAPT (0.55) | LMNAALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL29385190 | 0.74 | MAPT (0.55) | LMNAALDH1A1MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205079-B1 | ACID DISULFIMIDE TRIPHENODIOXAZINE DYES | BAYER AG (DE) | 1992-01-22 | — | — | EP | disclosed |
| EP-0205079-A2 | Acid disulfimide triphenodioxazine dyes | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |