Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691181 | 0.80 | PTPRG (0.51) | PTPRGMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9749314 | 0.76 | HSD17B10 (0.40) | KMT2AALDH1A1L3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL9748003 | 0.72 | PTGS1 (0.36) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL10432896 | 0.65 | SMN1; SMN2 (0.39) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL10432306 | 0.65 | ALDH1A1 (0.39) | ALDH1A1TDP1RAB9AMAPTTP53 | |
| SCHEMBL9368410 | 0.64 | L3MBTL1 (0.52) | MEN1KMT2AALDH1A1TDP1HTT | |
| SCHEMBL9228723 | 0.62 | PPIA (0.53) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL15189691 | 0.62 | RORB (0.44) | MEN1KMT2AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7830138 | 0.62 | PTPRG (1.00) | PTPRGMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL9852576 | 0.62 | KDM4E (0.34) | TDP1L3MBTL1RAB9ADAOKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |