Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361186 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2CA12CA1CA2CA3 | |
| SCHEMBL9749986 | 0.80 | LMNA (0.49) | POLBHSD17B10RAB9AGAAL3MBTL1 | |
| SCHEMBL9748847 | 0.67 | L3MBTL1 (0.45) | POLBALDH1A1CYP1A2HSD17B10HTT | |
| SCHEMBL10965043 | 0.67 | APEX1 (0.41) | SMN1; SMN2POLBALDH1A1HSD17B10HTT | |
| SCHEMBL16353744 | 0.66 | HTT (0.57) | SMN1; SMN2POLBALDH1A1HTTKDM4E | |
| SCHEMBL10688586 | 0.66 | APEX1 (0.44) | SMN1; SMN2POLBALDH1A1HSD17B10HTT | |
| SCHEMBL6191790 | 0.63 | CDK2 (0.62) | SMN1; SMN2CA12CA1CA2CA3 | |
| SCHEMBL7924409 | 0.62 | RAB9A (0.56) | SMN1; SMN2CYP1A2CYP2C9NPC1RAB9A | |
| SCHEMBL5849464 | 0.62 | ALDH1A1 (0.66) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL16353734 | 0.62 | MAPK1 (0.49) | POLBALDH1A1HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |